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DOPAMINE ANTAGONISTS
Descriptors Found:
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DeCS
Descriptor
English
:
Dopamine Antagonists
Descriptor
Spanish
:
Antagonistas de Dopamina
Descriptor
Portuguese
:
Antagonistas de Dopamina
Synonyms
English
:
Antagonists, Dopamine
Antagonists, Dopamine Receptor
Antagonists, Dopaminergic
Blockers, Dopamine
Dopamine Blockers
Dopamine Receptor Antagonists
Dopaminergic Antagonists
Receptor Antagonists, Dopamine
Tree Number:
D27.505.519.625.150.175
D27.505.696.577.150.175
Definition
English
:
Drugs that bind to but do not activate
DOPAMINE
RECEPTORS, thereby blocking the actions of
dopamine
or exogenous agonists. Many drugs used in the treatment of
psychotic disorders
(
ANTIPSYCHOTIC AGENTS
) are
dopamine antagonists
, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking
dopamine
receptors.
Dopamine antagonists
have been used for several other clinical purposes including as
ANTIEMETICS
, in the treatment of
Tourette syndrome
, and for
hiccup
.
Dopamine
receptor blockade is associated with
NEUROLEPTIC MALIGNANT SYNDROME.
History Note
English
:
95
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
32275
Unique Identifier:
D018492
Occurrence in VHL
:
Similar:
DeCS